No, there are nothing special you need to do or talk about.
The skin protects the head, and since children don't produce so much testosterone, they don't produce so much sebum (grease) from the sebaceous glands, so there are no o need to clean under the skin untill they hit puberty.
Some can't even withdraw the skin at young age, but that usually solves it self when he grows older (it was suppose to work so by design).
As older and sex, there are no big difference between cut and uncut.
Basically you can say it's like a clicker-pen, it peeks out when it need to.
Health wise it better because it gives more protection against urinary infection.
The sebum is also protecting against fungus and bacteria.
The disadvantage is that since the head don't get cleaned against the undies, as the cut one does, it requires cleaning (after puberty), but it's just to clean it during shower/bath, and there is nothing special, just water and soap..